Update on the latest in sports:

NFL-49ERS SMITH Alex Smith won't play against Broncos LONDON (AP) - We get word from London that a separated left shoulder will keep 49ers quarterback Alex Smith out of Sunday's game against the Denver Broncos in Wembley Stadium. Coach Mike Singletary says his No. 1 signal caller will be sidelined for 2 to 3 weeks and Troy Smith will start for the 1-6 Niners. Alex Smith was injured on a sack in the third quarter of last Sunday's 23-20 loss to the Carolina Panthers. David Carr replaced him, but was passed over for this weekend's game. Troy Smith was signed in December and has not yet played a game for the 49ers. MLB-WORLD SERIES 2010 Fall Classic debuts tonight SAN FRANCISCO (AP) - Game 1 of the World Series is set for this evening in San Francisco. The forecast is calling for cloudy skies and a gametime temperature in the 50s, with a slight chance of showers. The hometown Giants are chasing their first championship since leaving New York in 1958. They'll send Tim Lincecum (LIN'-sih-kuhm) to the mound to face Texas lefty Cliff Lee in a matchup of Cy Young winners. The Rangers are making their first appearance in the Fall Classic. They'll play Game 2 tomorrow in the City By The Bay, before heading to the Lone Star State for Games 3 and 4 on Saturday and Sunday, and, if necessary, Game 5 on Monday. Games 6 and 7 would be played back on the West coast. San Francisco has home-field advantage thanks to the National League's win in the All-Star game. MLB-METS/ALDERSON Mets reportedly pick Alderson NEW YORK (AP) - The New York Mets reportedly have settled on a general manager. Sports Illustrated reports on its website that the Mets have chosen Sandy Alderson to succeed Omar Minaya, who was dismissed this month after six seasons. Alderson interviewed with the Mets for a second time on Tuesday, one day after Josh Byrnes had his second interview with the team. Alderson formerly was president of the Oakland Athletics and chief executive officer of the San Diego Padres. The team declined to confirm to The Associated Press that Alderson will be named to the post. NBA-SCHEDULE Busy second night of NBA action UNDATED (AP) - One night after beating Miami in LeBron James' debut with the Heat on opening night, the Celtics are in Cleveland to take on King James' old club. Its' the Cavaliers' season debut. The Heat have moved on to Philadelphia for tonight's 76ers opener. The rest of the NBA schedule has New Jersey hosting Detroit, New York at Toronto, Memphis hosting Atlanta, Sacramento at Minnesota, New Orleans home to Milwaukee, Chicago at Oklahoma City, Charlotte at Dallas, San Antonio hosting Indiana Houston at Golden State, Portland at the L.A. Clippers and Denver home to Utah. After months of talk about Carmelo Anthony leaving Denver in a trade, the All-Star forward will still be in a Nuggets' uniform for tonight's season opener against the Jazz. NHL-SCHEDULE Penguins and Lightning look to protect slims leads UNDATED (AP) - There's a matchup of early season division leaders on tonight's six-game NHL schedule, with Tampa Bay playing host to Pittsburgh. The Lightning lead Washington by one point in the Southeast. The Capitals skate at Carolina. The Penguins are one point clear of the New York Islanders in the Atlantic. The Isles are in Montreal to face the Northeast co-leading Canadiens. The Stanley Cup champion Chicago Blackhawks will be out to avoid a third straight loss following a four-game winning streak when they host the Pacific Division-leading L.A. Kings, who've won five of six. New Jersey at San Jose rounds out the slate. The Devils have lost four of their last five outings. The Sharks are winless in their three games at home this season. TENNIS-DAVIS CUP/U.S. CAPTAIN Courier's lobbying pays off UNDATED (AP) - Jim Courier has been hired by the U.S. Tennis Association to lead the country's Davis Cup team. The four-time Grand Slam champion replaces Patrick McEnroe, who resigned last month. Courier had lobbied aggressively for the job after McEnroe announced he'd be leaving. McEnroe served as U.S. captain for 10 years, winning the 2007 Davis Cup to end the country's 12-year drought. As a player, Courier helped the U.S. win the Davis Cup in 1992 and 1995. The 40-year-old Courier retired from the professional tour in 2000 and was elected to the International Tennis Hall of Fame in 2005. Courier's 2011 debut as Davis Cup captain will come in the first round at Chile in March. If the Americans win, they would face Spain or Belgium in the July quarterfinals. HORSE RACING-BREEDERS' CUP ENTRIES Strong field for Breeders' Cup Classic UNDATED (AP) - Zenyatta will put her 19-0 record on the line when she defends her title in the $5 million Breeders' Cup Classic. The filly will be going against the boys for the second consecutive year. Zenyatta has been pre-entered in the Classic, along with 13 others. The list includes Preakness winner Lookin At Lucky and runner-up First Dude, Whitney winner Blame and Woodward and Metropolitan Mile winner Quality Road. Final entries and the post-position draw will be announced Tuesday. Zenyatta has won all five of her starts this year and will be looking to end her spectacular career with a victory in the 1 1/4-mile Classic. It will be her second start on dirt this year. She won the Apple Blossom for the second straight year at Arkansas' Oaklawn Park in April. BASEBALL-NUNS/CARD AUCTION Stunned Nuns BALTIMORE (AP) - Some nuns in Baltimore are making a splash in the sports-memorabilia world. They're auctioning off a rare, century-old Honus Wagner baseball card. The card was left to the School Sisters of Notre Dame by the brother of a deceased nun. The man had owned the card since 1936, and it was stowed away in a safe-deposit box. It's in poor condition, but any Wagner card from the T206 series, produced between 1909 and 1911, is highly prized by collectors. The card is expected to fetch between $150,000 and $200,000. Sister Virginia Muller had never heard of shortstop Honus Wagner and tells The Associated Press, "It just boggles your mind." She says proceeds from the sale will go to benefit the sisters' ministries in 35 countries. (Copyright 2010 by The Associated Press.  All Rights Reserved.) AP-NY-10-27-10 1054EDT